Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108280498Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (681 aa)    
Predicted Functional Partners:
LOC108266093
Thioredoxin domain-containing protein 3 homolog; Belongs to the NDK family.
    
 
 0.612
wdr90
WD repeat-containing protein 90.
    
 0.590
LOC108267017
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 
 0.556
LOC108275945
Junctophilin-2-like.
  
  
 
0.556
jph3
Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
  
  
 
0.555
LOC108270934
Junctophilin-3-like.
  
  
 
0.554
LOC108256670
Junctophilin-1-like.
  
  
 
0.550
lrguk
Leucine-rich repeat and guanylate kinase domain-containing protein isoform X1.
    
 
 0.531
LOC108280803
Rab5 GDP/GTP exchange factor-like.
    
 0.529
rabgef1
Rab5 GDP/GTP exchange factor isoform X2.
    
 0.529
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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