Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pde6aPhosphodiesterase. (858 aa)    
Predicted Functional Partners:
pde6g
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
   
 0.995
LOC108275843
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like.
   
 
 0.967
LOC108279216
Phosphodiesterase.
  
  
0.956
LOC108271583
Guanine nucleotide-binding protein G(T) subunit alpha-1.
   
 0.940
nt5e
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
 0.897
LOC108257427
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.896
LOC108265815
Guanine nucleotide-binding protein G(T) subunit alpha-2-like.
   
 0.884
ENSIPUP00000025550
Guanine nucleotide-binding protein G(t) subunit alpha-3-like.
   
 0.884
LOC108272812
Guanylate cyclase.
   
 0.881
adcy3
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.871
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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