Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxl18F-box/LRR-repeat protein 18. (765 aa)    
Predicted Functional Partners:
cul1
Cullin 1.
    
 0.952
LOC108280768
Cullin-1; Belongs to the cullin family.
    
 0.952
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.890
LOC108279000
E3 ubiquitin-protein ligase RBX1-like.
    
 0.711
rbx1
E3 ubiquitin-protein ligase RBX1.
    
 0.711
fbxl16
F-box/LRR-repeat protein 16.
    
 
 0.704
cul3
Cullin-3 isoform X1; Belongs to the cullin family.
    
 0.677
LOC108261246
Cullin-3.
    
 0.677
LOC108280845
Cullin-3-like isoform X1; Belongs to the cullin family.
    
 0.677
LOC108279751
F-box/LRR-repeat protein 14.
    
 0.632
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.