Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108263783Programmed cell death protein 4-like isoform X1. (469 aa)    
Predicted Functional Partners:
mtap
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
      
 0.686
if4a1
Eukaryotic initiation factor 4A-I.
   
 
 0.659
LOC108267852
Eukaryotic initiation factor 4A-II.
   
 
 0.659
eif4a2
Eukaryotic initiation factor 4A-II; Belongs to the DEAD box helicase family.
   
 
 0.659
eif4a3
Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family.
   
 
 0.650
reck
Reversion-inducing cysteine-rich protein with Kazal motifs.
      
 0.613
eif3a
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
 
 0.609
LOC108275724
CXXC-type zinc finger protein 4-like.
      
 0.572
LOC108275024
F-box/WD repeat-containing protein 11-like isoform X1.
    
 
 0.566
LOC108277126
F-box/WD repeat-containing protein 11 isoform X1.
    
 
 0.566
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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