Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rubcnlUncharacterized protein KIAA0226-like homolog isoform X2. (585 aa)    
Predicted Functional Partners:
uvrag
UV radiation resistance-associated gene protein.
    
 
 0.798
cwc25
pre-mRNA-splicing factor CWC25 homolog.
   
    0.735
acot11
Acyl-coenzyme A thioesterase 11 isoform X2.
   
    0.735
c24h1orf109
Uncharacterized protein c1orf109-like protein.
   
    0.735
ftsj1
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
   
    0.731
LOC108263125
Calcium homeostasis modulator protein 2-like.
   
    0.727
shd
SH2 domain-containing adapter protein D.
   
    0.699
LOC108269106
RUN and FYVE domain-containing protein 1-like.
    
 
 0.685
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
  
 0.666
lix1l
LIX1-like protein.
   
    0.654
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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