Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
noxo1NADPH oxidase organizer 1 isoform X1. (456 aa)    
Predicted Functional Partners:
LOC108264585
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
    
 0.997
ncf2
Neutrophil cytosol factor 2.
   
 0.953
LOC108255761
NADPH oxidase activator 1-like.
   
 0.953
nox4
NADPH oxidase 4 isoform X1.
   
 0.787
nox1
NADPH oxidase 1.
   
 0.737
xk
XK-related protein.
   
 0.699
LOC108259374
Cytochrome b-245 heavy chain.
   
 0.699
xkrx
XK-related protein.
   
 0.699
nox5
NADPH oxidase 5 isoform X1.
   
 0.662
duox1
Dual oxidase 1.
   
 0.662
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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