Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htra3Serine protease HTRA3. (465 aa)    
Predicted Functional Partners:
eci2
enoyl-CoA delta isomerase 2, mitochondrial isoform X1.
    
 0.666
ENSIPUP00000026885
annotation not available
    
 0.664
birc6
Baculoviral IAP repeat-containing protein 6.
    
 0.664
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.652
xiap
E3 ubiquitin-protein ligase XIAP isoform X2.
    
 
 0.648
LOC108269206
E3 ubiquitin-protein ligase XIAP-like isoform X1.
    
 
 0.648
tcp1
T-complex protein 1 subunit alpha.
   
 
 0.641
ephx2
Bifunctional epoxide hydrolase 2.
  
 
 0.634
LOC108275753
Non-specific lipid-transfer protein-like isoform X1.
    
  0.623
scp2
Non-specific lipid-transfer protein isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.
    
  0.623
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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