Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC108267758Protein FAM49B-like. (325 aa)    
Predicted Functional Partners:
LOC108273830
Ras-related C3 botulinum toxin substrate 1-like.
    
 0.926
LOC108257150
Ras-related C3 Botulinum toxin substrate 1.
    
 0.926
LOC108276437
Ras-related C3 Botulinum toxin substrate 2.
    
 0.926
rac3
Ras-related C3 botulinum toxin substrate 3.
    
 0.926
lrrc40
Leucine-rich repeat-containing protein 40.
     
 0.636
ddx1
ATP-dependent RNA helicase DDX1.
      
 0.564
LOC108278257
Testis-expressed sequence 2 protein-like isoform X2.
      
 0.488
klhl7
Kelch-like protein 7.
      
 0.476
aplp2
Amyloid-like protein 2 isoform X1.
     
 0.442
impdh1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.419
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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