Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
sec63Translocation protein SEC63 homolog. (763 aa)    
Predicted Functional Partners:
sec62
Translocation protein SEC62.
   
 0.999
sec61b
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 
 0.996
LOC108272151
Protein transport protein Sec61 subunit alpha-like 1.
   
 
 0.993
SEC61A1
Protein transport protein Sec61 subunit alpha-like 1.
   
 
 0.993
SEC61G
Protein transport protein Sec61 subunit gamma.
    
 
 0.983
LOC108256481
Protein transport protein Sec61 subunit gamma.
    
 
 0.983
hspa5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
  
 
 0.979
srpra
Signal recognition particle receptor subunit alpha isoform X1.
   
 
 0.966
hyou1
Hypoxia up-regulated protein 1.
  
 
 0.949
srp54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
  
 0.944
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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