Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zmat3Zinc finger matrin-type protein 3 isoform X1. (393 aa)    
Predicted Functional Partners:
riok3
Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
    
   0.784
plekha5
Pleckstrin homology domain-containing family A member 5 isoform X1.
    
 
 0.745
myct1
Myc target protein 1 isoform X1.
      
 0.703
mdm4
Protein Mdm4 isoform X2; Belongs to the MDM2/MDM4 family.
   
  
 0.620
sh2d5
SH2 domain-containing protein 5 isoform X1.
      
 0.615
fto
Alpha-ketoglutarate-dependent dioxygenase FTO isoform X1.
    
   0.613
prkra
Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1.
    
 
 0.612
tarbp2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 
 0.612
inka2
Protein FAM212B isoform X1.
      
 0.609
eps15
Epidermal growth factor receptor substrate 15 isoform X1.
    
  0.543
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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