ENSIPUP00000004606 protein (Ictalurus punctatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSIPUP00000004606

annotation not available (95 aa)

Predicted Functional Partners:

suds3

0.727

rce1

0.680

cdc25b

0.606

fau

0.605

ifih1

0.579

LOC108267915

0.567

tp53

0.567

dhx33

0.513

LOC108268191

0.512

brms1l

0.512

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSIPUP00000004606	LOC108267915	ENSIPUP00000004606	ENSIPUP00000028967	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.567
ENSIPUP00000004606	LOC108268191	ENSIPUP00000004606	ENSIPUP00000002400	annotation not available	Breast cancer metastasis-suppressor 1-like protein-A.	0.512
ENSIPUP00000004606	brms1l	ENSIPUP00000004606	ENSIPUP00000017915	annotation not available	Breast cancer metastasis-suppressor 1-like protein isoform X1.	0.512
ENSIPUP00000004606	cdc25b	ENSIPUP00000004606	ENSIPUP00000009221	annotation not available	M-phase inducer phosphatase 2.	0.606
ENSIPUP00000004606	dhx33	ENSIPUP00000004606	ENSIPUP00000017131	annotation not available	Putative ATP-dependent RNA helicase DHX33.	0.513
ENSIPUP00000004606	fau	ENSIPUP00000004606	ENSIPUP00000030170	annotation not available	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.605
ENSIPUP00000004606	ifih1	ENSIPUP00000004606	ENSIPUP00000019810	annotation not available	Interferon-induced helicase C domain-containing protein 1.	0.579
ENSIPUP00000004606	rce1	ENSIPUP00000004606	ENSIPUP00000026373	annotation not available	CAAX prenyl protease 2.	0.680
ENSIPUP00000004606	suds3	ENSIPUP00000004606	ENSIPUP00000026745	annotation not available	LOW QUALITY PROTEIN: sin3 histone deacetylase corepressor complex component SDS3.	0.727
ENSIPUP00000004606	tp53	ENSIPUP00000004606	ENSIPUP00000031919	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.567
LOC108267915	ENSIPUP00000004606	ENSIPUP00000028967	ENSIPUP00000004606	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	annotation not available	0.567
LOC108267915	cdc25b	ENSIPUP00000028967	ENSIPUP00000009221	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	M-phase inducer phosphatase 2.	0.476
LOC108267915	tp53	ENSIPUP00000028967	ENSIPUP00000031919	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.903
LOC108268191	ENSIPUP00000004606	ENSIPUP00000002400	ENSIPUP00000004606	Breast cancer metastasis-suppressor 1-like protein-A.	annotation not available	0.512
LOC108268191	suds3	ENSIPUP00000002400	ENSIPUP00000026745	Breast cancer metastasis-suppressor 1-like protein-A.	LOW QUALITY PROTEIN: sin3 histone deacetylase corepressor complex component SDS3.	0.856
brms1l	ENSIPUP00000004606	ENSIPUP00000017915	ENSIPUP00000004606	Breast cancer metastasis-suppressor 1-like protein isoform X1.	annotation not available	0.512
brms1l	suds3	ENSIPUP00000017915	ENSIPUP00000026745	Breast cancer metastasis-suppressor 1-like protein isoform X1.	LOW QUALITY PROTEIN: sin3 histone deacetylase corepressor complex component SDS3.	0.938
cdc25b	ENSIPUP00000004606	ENSIPUP00000009221	ENSIPUP00000004606	M-phase inducer phosphatase 2.	annotation not available	0.606
cdc25b	LOC108267915	ENSIPUP00000009221	ENSIPUP00000028967	M-phase inducer phosphatase 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.476
cdc25b	ifih1	ENSIPUP00000009221	ENSIPUP00000019810	M-phase inducer phosphatase 2.	Interferon-induced helicase C domain-containing protein 1.	0.444