Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdia3Protein disulfide-isomerase. (496 aa)    
Predicted Functional Partners:
LOC108265943
Calreticulin.
   
 0.992
LOC108280796
Calreticulin.
   
 0.982
calr3
Calreticulin.
   
 0.982
hspa5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
  
 0.955
tapbp
Tapasin isoform X2.
    
 0.945
hsp90b1
Endoplasmin.
   
 0.931
canx
Calnexin precursor.
   
 0.903
LOC108267688
Protein disulfide-isomerase.
  
  
 
0.901
LOC108273190
Protein disulfide-isomerase.
  
  
 
0.901
tap1
Antigen Peptide transporter 1.
   
 0.856
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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