Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sos2Son of sevenless homolog 2. (1258 aa)    
Predicted Functional Partners:
LOC108256494
Growth factor receptor-bound protein 2.
    
 0.996
grb2
Growth factor receptor-bound protein 2 isoform X1.
    
 0.992
nras
GTPase NRas.
   
 0.980
hras
GTPase HRas.
   
 0.979
LOC108274959
GTPase KRas isoform X1.
   
 0.975
LOC108258948
GTPase HRas-like isoform X2.
   
 0.975
LOC108259582
GTPase HRas.
   
 0.974
egfr
Receptor protein-tyrosine kinase.
    
 0.971
rras2
Ras-related protein R-Ras2.
   
 0.959
LOC108263592
Fibroblast growth factor receptor.
    
 0.959
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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