Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
zfand1AN1-type zinc finger protein 1. (270 aa)    
Predicted Functional Partners:
nsfl1c
NSFL1 cofactor p47.
    
 
 0.802
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.769
nploc4
Nuclear protein localization protein 4 homolog.
    
 
 0.731
faap100
Fanconi anemia core complex-associated protein 100.
    
 
 0.731
pum1
Pumilio homolog 1 isoform X1.
    
   0.725
psmc4
26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.
   
   0.714
psmd7
26S proteasome non-ATPase regulatory subunit 7.
   
 
 0.700
vcp
Transitional Endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.
   
 
 0.695
spata5
Spermatogenesis-associated protein 5.
   
 
 0.687
spata5l1
Spermatogenesis-associated protein 5-like protein 1.
   
 
 0.687
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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