Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
pde3bPhosphodiesterase. (1091 aa)    
Predicted Functional Partners:
LOC108264340
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.944
LOC108259077
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.944
akt3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.944
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.944
adsl
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.901
ak3
GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
     
  0.900
aprt
Adenine phosphoribosyltransferase.
     
  0.900
LOC108276068
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.892
adk
Adenosine kinase isoform X1.
     
 0.865
slc46a1
Proton-coupled folate transporter.
      
 0.837
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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