Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gli3Transcriptional activator GLI3 isoform X1. (1623 aa)    
Predicted Functional Partners:
sufu
Suppressor of fused homolog.
    
 0.994
kif7
Kinesin-like protein KIF7 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.990
spop
Speckle-type POZ protein.
   
 0.979
LOC108270802
Speckle-type POZ protein-like B.
   
 0.975
spopl
Speckle-type POZ protein-like.
   
 0.975
smo
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.975
LOC108267323
cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.
    
 0.974
ptch2
Protein patched homolog 2.
   
 0.968
kapca
Camp-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.
    
 0.966
prkaca
cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.966
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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