Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
stambpSTAM-binding protein. (442 aa)    
Predicted Functional Partners:
stam
Signal transducing adapter molecule 1.
    
 0.938
stam2
Signal transducing adapter molecule 2.
    
 0.934
rps27a
Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]
   
 0.895
gak
cyclin-G-associated kinase isoform X2.
    
  0.891
chmp2a
Charged multivesicular body protein 2A.
   
 
 0.821
chmp3
Charged multivesicular body protein 3.
   
 
 0.788
uba52
ubiquitin-60S ribosomal protein L40 isoform X1.
   
 0.787
chmp1a
Charged multivesicular body protein 1A.
   
 
 0.786
bmp2k
BMP-2-inducible protein kinase isoform X2.
    
   0.734
uchl5
Ubiquitin carboxyl-terminal hydrolase.
   
 0.716
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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