Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (419 aa)    
Predicted Functional Partners:
gnas
Guanine nucleotide-binding protein G(S) subunit alpha.
    
 0.926
LOC108262790
Guanine nucleotide-binding protein G(Olf) subunit alpha-like.
    
 0.746
htr3b
5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.746
gnal
Guanine Nucleotide-binding protein G(olf) subunit alpha.
    
 0.746
LOC108263758
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.527
rhobtb3
Rho-related BTB domain-containing protein 3 isoform X2.
    
  0.517
cacng5
Voltage-dependent calcium channel gamma-5 subunit.
  
  
 0.504
LOC108275568
Voltage-dependent calcium channel gamma-5 subunit-like.
  
  
 0.500
LOC108278607
5-hydroxytryptamine receptor 3A-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.473
fam126a
Hyccin.
    
 
 0.464
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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