Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108277383Mitochondrial uncoupling protein 2-like; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)    
Predicted Functional Partners:
sirt7
NAD-dependent protein deacetylase sirtuin-7.
      
 0.826
sirt5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
    
 
 0.654
sirt6
NAD-dependent protein deacetylase sirtuin-6 isoform X1.
      
 0.637
fis1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
      
 0.620
prdx3
Thioredoxin-dependent peroxide reductase, mitochondrial.
      
 0.572
LOC108271948
Thyrotropin subunit beta-like.
   
  
 0.572
slc25a27
Mitochondrial uncoupling protein 4 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
     
  0.572
ppargc1a
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X5.
   
 0.554
tmem26
Transmembrane protein 26.
      
 0.547
acadm
Medium-chain specific Acyl-CoA dehydrogenase, mitochondrial.
      
 0.530
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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