Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bcar1Breast cancer anti-estrogen resistance protein 1 isoform X4. (883 aa)    
Predicted Functional Partners:
crkl
Crk-like protein.
    
 0.983
crk
Adapter molecule crk.
    
 0.983
CRK
Adapter molecule crk-like.
    
 0.983
ptk2
Focal adhesion kinase 1 isoform X5; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.980
LOC108267913
Focal adhesion kinase 1-like isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.980
dock1
Dedicator of cytokinesis protein 1; Belongs to the DOCK family.
    
 0.953
LOC108270138
Protein-tyrosine kinase 2-beta-like isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.819
LOC108258133
Protein-tyrosine kinase 2-beta-like isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.819
LOC108273866
LOW QUALITY PROTEIN: vinculin-like.
    
 0.803
vcl
Vinculin isoform X1.
    
 0.803
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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