Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nr4a2Nuclear receptor subfamily 4 group A member 2. (619 aa)    
Predicted Functional Partners:
ncor1
Nuclear receptor corepressor 1 isoform X16.
    
 0.569
ncor2
Nuclear receptor corepressor 2 isoform X2.
    
 0.562
LOC108267470
Apoptosis regulator Bcl-2-like.
   
 
 0.508
pitx3
Homeobox protein.
    
 
 0.503
LOC108264340
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.493
LOC108259077
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.493
akt3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.493
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.493
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
  0.469
nrp2
Neuropilin; Belongs to the neuropilin family.
      
 0.449
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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