Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cskTyrosine-protein kinase. (449 aa)    
Predicted Functional Partners:
pag1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1.
    
 0.922
LOC108276232
Tyrosine-protein phosphatase non-receptor type 22-like isoform X1.
   
 0.766
shc1
SHC-transforming protein 1 isoform X2.
    
 0.765
SHC3
SHC-transforming protein 3-like.
    
 0.765
cav3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 0.764
LOC108265862
Tyrosine-protein phosphatase non-receptor type 18-like isoform X1.
   
 0.752
ptpn12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 0.752
LOC108265409
Uncharacterized protein LOC108265409.
   
 0.746
LOC108265853
Leupaxin-like isoform X2.
   
 0.746
tgfb1i1
Transforming growth factor beta-1-induced transcript 1 protein isoform X1; Belongs to the paxillin family.
   
 0.746
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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