Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108274314Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)    
Predicted Functional Partners:
LOC100304475
3 beta-hydroxysteroid dehydrogenase/Delta 5--4-isomerase; Belongs to the 3-beta-HSD family.
   
 
 0.938
LOC108278029
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.924
LOC108267573
Cholesterol 7-alpha-monooxygenase-like isoform X2.
   
 
 0.924
sts
Steryl-sulfatase isoform X1.
   
 
 0.917
LOC108275468
Steroid 17-alpha-hydroxylase/17,20 lyase-like isoform X1; Belongs to the cytochrome P450 family.
   
 
 0.912
LOC108261472
Steroid 21-hydroxylase-like; Belongs to the cytochrome P450 family.
   
 
 0.912
cyp17
Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
   
 
 0.912
LOC108270649
25-hydroxycholesterol 7-alpha-hydroxylase-like isoform X1; Belongs to the cytochrome P450 family.
     
 0.911
LOC108258748
Cytochrome P450 3A30-like.
   
 
 0.910
LOC108258760
Cytochrome P450 3A30-like.
   
 
 0.910
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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