STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr-5Toll-like receptor 5 precursor. (647 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.984
LOC108275978
Toll-like receptor 5; Belongs to the Toll-like receptor family.
  
  
 
0.900
TLR5
Toll-like receptor 5; Belongs to the Toll-like receptor family.
  
  
 
0.900
unc93b1
Protein unc-93 homolog B1.
    
 0.714
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.713
LOC108272691
Toll-like receptor 2 type-2 isoform X1; Belongs to the Toll-like receptor family.
   
 0.652
irak1
Interleukin-1 receptor-associated kinase 1 isoform X4.
   
 0.650
ENSIPUP00000000585
annotation not available
   
 0.629
LOC108273140
Lymphocyte antigen 86-like.
   
 0.629
LOC100304977
TIR-containing adaptor molecule.
   
 0.627
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.