STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ube2aUbiquitin conjugating enzyme E2 A. (122 aa)    
Predicted Functional Partners:
leo1
RNA polymerase-associated protein LEO1.
   
 0.960
LOC108255212
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.934
ub2v1
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.934
rad18
E3 ubiquitin-protein ligase RAD18 isoform X1.
    
 0.930
rps27a
Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]
   
 0.876
trip12
E3 ubiquitin-protein ligase TRIP12.
   
 0.863
LOC108269267
E3 ubiquitin protein ligase.
   
 0.855
LOC108273672
E3 ubiquitin protein ligase.
   
 0.855
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.828
LOC108272095
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.815
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.