STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (409 aa)    
Predicted Functional Partners:
epm2a
EPM2A glucan phosphatase, laforin.
    
 0.936
adam23
ADAM metallopeptidase domain 23.
      
 0.660
agl
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a.
    
 
 0.606
neu1
Neuraminidase 1.
      
 0.581
mlst8
WD_REPEATS_REGION domain-containing protein.
      
 0.497
Dhx57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57.
    
 0.465
LOC105007707
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
    
 0.435
gys2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
    
 0.435
LOC105030542
ADAM metallopeptidase domain 11.
      
 0.420
LOC105013332
Uncharacterized protein.
      
 0.420
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.