Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSELUP00000001709SRY-box transcription factor 3. (166 aa)    
Predicted Functional Partners:
LOC105014844
POU domain protein.
    
 0.961
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.842
sall4
Spalt-like transcription factor 4.
   
 0.835
AMHR2
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.833
klf17
Kruppel-like factor 17.
    
 0.779
zeb1
Zinc finger E-box binding homeobox 1b.
    
 0.716
prdm14
PR domain containing 14.
    
 0.637
LOC105027178
Lin-28 homolog A.
    
 0.618
LOC105019534
Nanog homeobox.
      
 0.617
spi1
Spi-1 proto-oncogene b.
      
 0.617
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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