STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105011406Si:ch73-60h1.1; Belongs to the protein kinase superfamily. (483 aa)    
Predicted Functional Partners:
hdac4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.905
LOC105023749
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.905
camk4
Calcium/calmodulin-dependent protein kinase IV; Belongs to the protein kinase superfamily.
  
  
 
0.901
LOC105013934
Calmodulin-like 4a.
   
 0.873
LOC105017693
Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.
   
 0.866
LOC105018659
Calmodulin-like 4b.
   
 0.755
CALML6
Calmodulin like 6.
   
 0.652
calm3
Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.
   
 0.633
LOC105013370
Uncharacterized protein.
   
 0.633
LOC105028068
Calmodulin.
   
 0.633
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.