STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TicrrTreslin_N domain-containing protein. (1814 aa)    
Predicted Functional Partners:
topbp1
DNA topoisomerase II binding protein 1.
    
 
 0.899
fbl
Fibrillarin.
   
 
 0.872
ENSELUP00000037811
BRCT domain-containing protein.
    
 0.822
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
  
 0.776
ENSELUP00000006512
Transducin (beta)-like 3.
   
 
 0.774
exo1
Exonuclease 1.
  
 
 0.767
wdr36
WD repeat domain 36.
   
 
 0.746
LOC105019722
PWP2 small subunit processome component.
   
 
 0.733
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 
 0.728
mtbp
MDM2 binding protein.
   
 0.723
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.