STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105021981Uncharacterized protein; Belongs to the cytochrome P450 family. (495 aa)    
Predicted Functional Partners:
aasdh
Aminoadipate-semialdehyde dehydrogenase.
  
 0.607
wrn
WRN RecQ like helicase.
    
 0.583
ndufab1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.538
nbn
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.536
LOC105016143
BRCA1 associated RING domain 1.
    
 0.523
LOC105010533
Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
   
 0.505
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.473
exo1
Exonuclease 1.
   
 0.441
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 0.433
LOC105011230
RAD50 homolog, double strand break repair protein.
    
 0.426
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.