Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC105018412Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (475 aa)    
Predicted Functional Partners:
kng1
Uncharacterized protein.
     
  0.900
LOC105014514
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.719
LOC105019863
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.719
GNA14
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.719
LOC105014461
Uncharacterized protein.
    
 0.719
LOC105027929
Uncharacterized protein.
    
 0.719
LOC105011594
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.719
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
 0.714
gnb2
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
 0.714
LOC105025424
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
 0.714
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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