STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRD3Bromodomain containing 3. (729 aa)    
Predicted Functional Partners:
LOC114838787
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.706
taf7l
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 
 0.694
dmap1
DNA methyltransferase 1 associated protein 1.
    
 
 0.584
e2f1
E2F transcription factor 1.
    
 
 0.571
nsd3
Nuclear receptor binding SET domain protein 3.
   
 
 0.565
jmjd6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
    
 
 0.561
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
   
 
 0.557
taf1
Transcription initiation factor TFIID subunit.
    
 
0.554
LOC105025106
E1A binding protein p300 a.
   
0.493
ENSELUP00000000119
Uncharacterized protein.
    
 
 0.489
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.