node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSELUP00000023572 | HDAC1 | ENSELUP00000023572 | ENSELUP00000027122 | PHD finger protein 21Aa. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.657 |
ENSELUP00000023572 | KDM1B | ENSELUP00000023572 | ENSELUP00000007291 | PHD finger protein 21Aa. | Lysine demethylase 1B. | 0.604 |
ENSELUP00000023572 | LOC105021930 | ENSELUP00000023572 | ENSELUP00000041906 | PHD finger protein 21Aa. | Amine oxidase. | 0.558 |
ENSELUP00000023572 | LOC105024174 | ENSELUP00000023572 | ENSELUP00000037953 | PHD finger protein 21Aa. | Amine oxidase. | 0.558 |
ENSELUP00000023572 | LOC105030237 | ENSELUP00000023572 | ENSELUP00000019105 | PHD finger protein 21Aa. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.657 |
ENSELUP00000023572 | Rest | ENSELUP00000023572 | ENSELUP00000024544 | PHD finger protein 21Aa. | Uncharacterized protein. | 0.592 |
ENSELUP00000023572 | hmg20b | ENSELUP00000023572 | ENSELUP00000038767 | PHD finger protein 21Aa. | High mobility group 20B. | 0.931 |
ENSELUP00000023572 | kdm1a | ENSELUP00000023572 | ENSELUP00000014706 | PHD finger protein 21Aa. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.932 |
ENSELUP00000023572 | rcor1 | ENSELUP00000023572 | ENSELUP00000003199 | PHD finger protein 21Aa. | REST corepressor 1. | 0.738 |
ENSELUP00000023572 | znf217 | ENSELUP00000023572 | ENSELUP00000004441 | PHD finger protein 21Aa. | Zinc finger protein 217. | 0.583 |
HDAC1 | ENSELUP00000023572 | ENSELUP00000027122 | ENSELUP00000023572 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | PHD finger protein 21Aa. | 0.657 |
HDAC1 | KDM1B | ENSELUP00000027122 | ENSELUP00000007291 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine demethylase 1B. | 0.677 |
HDAC1 | LOC105021930 | ENSELUP00000027122 | ENSELUP00000041906 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.677 |
HDAC1 | LOC105024174 | ENSELUP00000027122 | ENSELUP00000037953 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Amine oxidase. | 0.677 |
HDAC1 | LOC105030237 | ENSELUP00000027122 | ENSELUP00000019105 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.900 |
HDAC1 | Rest | ENSELUP00000027122 | ENSELUP00000024544 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Uncharacterized protein. | 0.604 |
HDAC1 | hmg20b | ENSELUP00000027122 | ENSELUP00000038767 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | High mobility group 20B. | 0.712 |
HDAC1 | kdm1a | ENSELUP00000027122 | ENSELUP00000014706 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.883 |
HDAC1 | rcor1 | ENSELUP00000027122 | ENSELUP00000003199 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 1. | 0.807 |
HDAC1 | znf217 | ENSELUP00000027122 | ENSELUP00000004441 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Zinc finger protein 217. | 0.452 |