STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfn1Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (745 aa)    
Predicted Functional Partners:
prkn
RBR-type E3 ubiquitin transferase.
    
 0.921
MFN1
Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
  
  
 
0.901
pink1
PTEN induced kinase 1.
   
 0.850
gak
Cyclin G associated kinase.
   
 0.830
vdac1
Voltage-dependent anion channel 1.
   
 0.744
atg5
Autophagy protein 5; Involved in autophagic vesicle formation.
     
 0.733
ENSELUP00000030223
Uncharacterized protein.
    
 
 0.715
ENSELUP00000038179
Intersectin 2b.
    
 
 0.715
sqstm1
Sequestosome 1.
     
 0.695
atg12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
     
 0.693
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.