gpr135 protein (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

gpr135

G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (420 aa)

Predicted Functional Partners:

Npff

0.598

LOC105022791

0.547

fbxo34

0.511

LOC105016280

0.461

gnao1

0.461

LOC105018176

0.458

ENSELUP00000016919

0.457

grk3

0.455

grk6

0.455

GRK1

0.455

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSELUP00000016919	GRK1	ENSELUP00000016919	ENSELUP00000021769	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.512
ENSELUP00000016919	LOC105018176	ENSELUP00000016919	ENSELUP00000021457	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	Guanine nucleotide binding protein (G protein), beta 5a.	0.781
ENSELUP00000016919	LOC105022791	ENSELUP00000016919	ENSELUP00000021088	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.761
ENSELUP00000016919	Npff	ENSELUP00000016919	ENSELUP00000015652	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	Neuropeptide FF-amide peptide precursor like.	0.556
ENSELUP00000016919	gpr135	ENSELUP00000016919	ENSELUP00000003531	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.457
ENSELUP00000016919	grk3	ENSELUP00000016919	ENSELUP00000003736	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.512
ENSELUP00000016919	grk6	ENSELUP00000016919	ENSELUP00000010719	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.512
GRK1	ENSELUP00000016919	ENSELUP00000021769	ENSELUP00000016919	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	0.512
GRK1	LOC105018176	ENSELUP00000021769	ENSELUP00000021457	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Guanine nucleotide binding protein (G protein), beta 5a.	0.619
GRK1	LOC105022791	ENSELUP00000021769	ENSELUP00000021088	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.603
GRK1	gpr135	ENSELUP00000021769	ENSELUP00000003531	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.455
LOC105016280	LOC105018176	ENSELUP00000011692	ENSELUP00000021457	Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.	Guanine nucleotide binding protein (G protein), beta 5a.	0.657
LOC105016280	LOC105022791	ENSELUP00000011692	ENSELUP00000021088	Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.672
LOC105016280	gpr135	ENSELUP00000011692	ENSELUP00000003531	Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.461
LOC105018176	ENSELUP00000016919	ENSELUP00000021457	ENSELUP00000016919	Guanine nucleotide binding protein (G protein), beta 5a.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3.	0.781
LOC105018176	GRK1	ENSELUP00000021457	ENSELUP00000021769	Guanine nucleotide binding protein (G protein), beta 5a.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.619
LOC105018176	LOC105016280	ENSELUP00000021457	ENSELUP00000011692	Guanine nucleotide binding protein (G protein), beta 5a.	Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.	0.657
LOC105018176	LOC105022791	ENSELUP00000021457	ENSELUP00000021088	Guanine nucleotide binding protein (G protein), beta 5a.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.875
LOC105018176	gnao1	ENSELUP00000021457	ENSELUP00000036788	Guanine nucleotide binding protein (G protein), beta 5a.	Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a.	0.657
LOC105018176	gpr135	ENSELUP00000021457	ENSELUP00000003531	Guanine nucleotide binding protein (G protein), beta 5a.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.458