ntn1 protein (Esox lucius) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

Experiments

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[Homology]

Score

ntn1

Netrin 1a. (603 aa)

Predicted Functional Partners:

Dcc

0.823

ENSELUP00000041245

0.823

igdcc4

0.816

ENSELUP00000036695

0.774

draxin

0.644

LOC105012757

0.618

LOC105031064

0.618

ENSELUP00000037496

0.618

fndc1

0.589

LOC105030490

0.583

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dcc	ENSELUP00000036695	ENSELUP00000014673	ENSELUP00000036695	DCC netrin 1 receptor.	Unc-5 netrin receptor B.	0.610
Dcc	LOC105030490	ENSELUP00000014673	ENSELUP00000004169	DCC netrin 1 receptor.	Down syndrome cell adhesion molecule a.	0.539
Dcc	draxin	ENSELUP00000014673	ENSELUP00000010369	DCC netrin 1 receptor.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.	0.802
Dcc	ntn1	ENSELUP00000014673	ENSELUP00000005000	DCC netrin 1 receptor.	Netrin 1a.	0.823
ENSELUP00000036695	Dcc	ENSELUP00000036695	ENSELUP00000014673	Unc-5 netrin receptor B.	DCC netrin 1 receptor.	0.610
ENSELUP00000036695	ENSELUP00000041245	ENSELUP00000036695	ENSELUP00000041245	Unc-5 netrin receptor B.	Neogenin 1b.	0.610
ENSELUP00000036695	igdcc4	ENSELUP00000036695	ENSELUP00000017465	Unc-5 netrin receptor B.	Immunoglobulin superfamily, DCC subclass, member 4.	0.446
ENSELUP00000036695	ntn1	ENSELUP00000036695	ENSELUP00000005000	Unc-5 netrin receptor B.	Netrin 1a.	0.774
ENSELUP00000037496	draxin	ENSELUP00000037496	ENSELUP00000010369	Immunoglobulin superfamily, DCC subclass, member 3.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.	0.600
ENSELUP00000037496	ntn1	ENSELUP00000037496	ENSELUP00000005000	Immunoglobulin superfamily, DCC subclass, member 3.	Netrin 1a.	0.618
ENSELUP00000041245	ENSELUP00000036695	ENSELUP00000041245	ENSELUP00000036695	Neogenin 1b.	Unc-5 netrin receptor B.	0.610
ENSELUP00000041245	LOC105030490	ENSELUP00000041245	ENSELUP00000004169	Neogenin 1b.	Down syndrome cell adhesion molecule a.	0.539
ENSELUP00000041245	draxin	ENSELUP00000041245	ENSELUP00000010369	Neogenin 1b.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.	0.802
ENSELUP00000041245	ntn1	ENSELUP00000041245	ENSELUP00000005000	Neogenin 1b.	Netrin 1a.	0.823
LOC105012757	draxin	ENSELUP00000013603	ENSELUP00000010369	Si:ch211-57n23.4.	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.	0.600
LOC105012757	ntn1	ENSELUP00000013603	ENSELUP00000005000	Si:ch211-57n23.4.	Netrin 1a.	0.618
LOC105030490	Dcc	ENSELUP00000004169	ENSELUP00000014673	Down syndrome cell adhesion molecule a.	DCC netrin 1 receptor.	0.539
LOC105030490	ENSELUP00000041245	ENSELUP00000004169	ENSELUP00000041245	Down syndrome cell adhesion molecule a.	Neogenin 1b.	0.539
LOC105030490	igdcc4	ENSELUP00000004169	ENSELUP00000017465	Down syndrome cell adhesion molecule a.	Immunoglobulin superfamily, DCC subclass, member 4.	0.479
LOC105030490	ntn1	ENSELUP00000004169	ENSELUP00000005000	Down syndrome cell adhesion molecule a.	Netrin 1a.	0.583