STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HaspinProtein kinase domain-containing protein. (949 aa)    
Predicted Functional Partners:
cdca5
Cell division cycle associated 5.
   
  
 0.668
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.655
sgo1
Shugoshin_C domain-containing protein.
   
  
 0.589
incenp
Uncharacterized protein.
   
  
 0.584
aurka
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.537
LOC105007115
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 
 0.537
cdca8
Cell division cycle associated 8.
   
  
 0.512
ENSELUP00000016758
BUB1 N-terminal domain-containing protein.
   
 
 0.481
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 
 0.481
LOC105023383
DSN1 component of MIS12 kinetochore complex.
   
  
 0.459
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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