Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
HaspinProtein kinase domain-containing protein. (949 aa)    
Predicted Functional Partners:
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.777
incenp
Uncharacterized protein.
   
  
 0.738
sgo1
Shugoshin_C domain-containing protein.
   
  
 0.724
LOC105031550
Baculoviral IAP repeat containing 5a.
   
 
 0.699
amt
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
      
 0.697
ENSELUP00000007776
Regulatory associated protein of MTOR, complex 1.
    
   0.695
pbk
PDZ binding kinase.
   
  
 0.689
cdca8
Cell division cycle associated 8.
   
  
 0.686
knl1
Knl1_RWD_C domain-containing protein.
   
  
 0.660
ENSELUP00000001334
Zwilch kinetochore protein.
   
  
 0.648
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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