STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC114833804ZnMc domain-containing protein. (469 aa)    
Predicted Functional Partners:
timp2
TIMP metallopeptidase inhibitor 2a.
   
 0.626
LOC105013051
TIMP metallopeptidase inhibitor 2b.
   
 0.601
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.553
LOC105021572
Matrix metallopeptidase 14b (membrane-inserted).
  
0.501
ENSELUP00000021439
Matrix metallopeptidase 15b.
  
0.495
dcn
Decorin; May affect the rate of fibrils formation.
   
 0.491
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.483
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 3.
    
 0.457
cd44
Link domain-containing protein.
   
 0.447
LOC105016805
Opticin.
    
  0.440
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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