STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105013606Uncharacterized protein; Belongs to the BI1 family. (301 aa)    
Predicted Functional Partners:
LOC105013406
Desumoylating isopeptidase 1a.
    
   0.876
LOC105025073
Desumoylating isopeptidase 1b.
    
   0.738
GHITM
Growth hormone inducible transmembrane protein; Belongs to the BI1 family.
   
  
 0.591
LOC105031436
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.587
LOC105015909
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.587
pdcd5
Uncharacterized protein.
   
  
 0.541
desi2
Desumoylating isopeptidase 2.
    
   0.515
LOC105025533
DUF862 domain-containing protein.
    
   0.515
lig1
DNA ligase.
      
 0.512
pcmt1
Protein-L-isoaspartate (D-aspartate) O-methyltransferase.
      
 0.489
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.