Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sox10SRY-box transcription factor 10. (479 aa)    
Predicted Functional Partners:
foxd3
Forkhead box D3.
    
 0.937
olig2
Oligodendrocyte lineage transcription factor 2.
   
 
 0.879
mitf
Melanocyte inducing transcription factor a.
    
 0.855
tyrp1
Tyrosinase related protein 1.
    
 0.783
ENSELUP00000006198
Paired box 3a.
   
 0.754
pax3
Paired box 3b.
   
 0.754
egr2
Early growth response 2b.
    
 0.751
olig1
Oligodendrocyte transcription factor 1.
   
 
 0.745
SNAI2
Snail family transcriptional repressor 2.
    
 
 0.716
LOC105013841
Paired box 7.
   
 0.707
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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