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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sox10SRY-box transcription factor 10. (479 aa)    
Predicted Functional Partners:
mitf
Melanocyte inducing transcription factor a.
    
 
 0.686
foxd3
Forkhead box D3.
   
 0.679
egr2
Early growth response 2b.
    
 0.676
olig2
Oligodendrocyte lineage transcription factor 2.
   
 0.643
olig1
Oligodendrocyte transcription factor 1.
   
 0.609
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.571
tyr
Tyrosinase.
    
 0.571
SNAI2
Snail family transcriptional repressor 2.
   
 
 0.563
LOC105015556
Cholinergic receptor, nicotinic, alpha 3.
      
 0.558
sox5
SRY-box transcription factor 5.
    
0.539
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.