STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfc4Replication factor C (activator 1) 4. (376 aa)    
Predicted Functional Partners:
rfc5
AAA domain-containing protein.
  
0.999
rad17
RAD17 checkpoint clamp loader component.
   
 0.999
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.999
rfc2
Replication factor C (activator 1) 2.
  
0.999
ENSELUP00000030130
Replication factor C subunit 1.
   
0.999
rfc3
Replication factor C (activator 1) 3.
   
0.999
LOC105013139
ATPase family AAA domain containing 5a.
   
 0.990
hus1
Checkpoint protein; Belongs to the HUS1 family.
   
 0.990
ENSELUP00000017019
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).
   
 0.988
rad1
Cell cycle checkpoint protein RAD1.
   
 0.987
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.