STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccne2Cyclin E2; Belongs to the cyclin family. (398 aa)    
Predicted Functional Partners:
cdkn1c
Cyclin-dependent kinase inhibitor 1Ca.
   
 0.990
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.990
rb1
Retinoblastoma 1.
   
 0.986
skp1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.985
cdkn1b
Cyclin-dependent kinase inhibitor 1Bb.
   
 0.983
LOC105017129
Cyclin-dependent kinase inhibitor 1A.
   
 0.983
LOC105029077
Cyclin-dependent kinase inhibitor 1D.
   
 0.983
LOC105026604
Cyclin-dependent kinase inhibitor 1Cb.
   
 0.983
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.982
LOC105023450
RB_A domain-containing protein.
   
 0.981
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.