STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdrd9Tudor domain containing 9. (1324 aa)    
Predicted Functional Partners:
ENSELUP00000030223
Uncharacterized protein.
    
  0.961
ENSELUP00000038179
Intersectin 2b.
    
  0.961
piwil2
Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 0.838
piwil1
Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 0.834
Itsn1
Intersectin 1 (SH3 domain protein).
    
  0.799
LOC105029770
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.785
LOC105021137
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.785
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.769
LOC105010881
UTP14C small subunit processome component.
   
 0.758
pdcd11
Programmed cell death 11.
  
 0.730
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.