STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1273 aa)    
Predicted Functional Partners:
LOC105014514
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.958
GNA14
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.958
LOC105014461
Uncharacterized protein.
    
 0.958
LOC105027929
Uncharacterized protein.
    
 0.955
LOC105027928
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.948
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
0.947
gprc6a
G protein-coupled receptor, class C, group 6, member A.
     
 0.926
LOC105007313
ANF_receptor domain-containing protein.
     
 0.926
casr
Calcium-sensing receptor.
     
 0.925
itpr2
Inositol 1,4,5-trisphosphate receptor, type 2.
   
 0.921
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.