STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105018992Sphingosine kinase 2. (902 aa)    
Predicted Functional Partners:
sgpl1
Sphingosine-1-phosphate lyase 1.
  
 0.966
LOC105006219
Neutral ceramidase.
    
 0.955
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.950
acer3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.948
acer1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.948
kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.946
LOC105015553
Sphingosine-1-phosphate phosphatase 1.
   
 0.942
LOC105017650
Si:ch211-212g7.6.
   
 0.942
SGPP2
Sphingosine-1-phosphate phosphatase 2.
   
 0.942
LOC105026133
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
     
  0.935
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.