STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105014676Tyrosine-protein kinase. (1117 aa)    
Predicted Functional Partners:
ENSELUP00000013755
Suppressor of cytokine signaling 3a.
   
 0.968
LOC105021322
Suppressor of cytokine signaling 3.
   
 0.968
lepr
Leptin receptor.
    
 0.968
LOC105022527
Signal transducer and activator of transcription.
   
 0.963
stat3
Signal transducer and activator of transcription.
   
 0.958
ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.953
LOC105013921
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.953
LOC105031504
Uncharacterized protein.
    
  0.914
ifngr1
Fibronectin type-III domain-containing protein.
     
 0.908
jak2
Tyrosine-protein kinase.
  
  
 
0.901
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.