STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (443 aa)    
Predicted Functional Partners:
LOC105027836
CASP2 and RIPK1 domain containing adaptor with death domain.
    
0.964
LOC105018117
BH3 interacting domain death agonist.
     
 0.902
ENSELUP00000042673
P53-induced death domain protein 1.
    
 0.896
apaf1
Apoptotic peptidase activating factor 1.
    
 0.869
xiap
X-linked inhibitor of apoptosis.
   
 0.783
cenpn
Centromere protein N.
   
 0.783
cenpi
Centromere protein I.
   
 0.765
cenpq
Uncharacterized protein.
   
 0.750
cenpp
Centromere protein P.
   
 0.744
cenpm
Centromere protein M.
   
 0.738
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.