STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105030826Matrix metallopeptidase 11. (501 aa)    
Predicted Functional Partners:
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 0.721
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.622
LOC105013051
TIMP metallopeptidase inhibitor 2b.
   
 0.579
timp2
TIMP metallopeptidase inhibitor 2a.
   
 0.579
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 3.
    
 0.440
dcn
Decorin; May affect the rate of fibrils formation.
    
 0.409
ENSELUP00000039671
ZnMc domain-containing protein.
  
0.409
LOC114833804
ZnMc domain-containing protein.
  
0.404
LOC105005972
ZnMc domain-containing protein.
  
0.400
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.