LOC105019751 protein (Esox lucius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC105019751

Coagulation factor VII. (482 aa)

Predicted Functional Partners:

tdo2

0.870

f2

0.770

serpinc1

0.739

serpina10

0.646

f5

0.621

LOC105024430

0.621

LOC105031614

0.599

LOC105009497

0.599

met

0.599

LOC105021910

0.581

Your Current Organism:

Esox lucius

NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105009497	LOC105019751	ENSELUP00000024048	ENSELUP00000025649	Uncharacterized protein.	Coagulation factor VII.	0.599
LOC105009497	LOC105031614	ENSELUP00000024048	ENSELUP00000002859	Uncharacterized protein.	Macrophage stimulating 1 receptor b.	0.710
LOC105009497	f2	ENSELUP00000024048	ENSELUP00000023415	Uncharacterized protein.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.606
LOC105009497	met	ENSELUP00000024048	ENSELUP00000034052	Uncharacterized protein.	MET proto-oncogene, receptor tyrosine kinase.	0.704
LOC105019751	LOC105009497	ENSELUP00000025649	ENSELUP00000024048	Coagulation factor VII.	Uncharacterized protein.	0.599
LOC105019751	LOC105021910	ENSELUP00000025649	ENSELUP00000018165	Coagulation factor VII.	Uncharacterized protein.	0.581
LOC105019751	LOC105024430	ENSELUP00000025649	ENSELUP00000029003	Coagulation factor VII.	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	0.621
LOC105019751	LOC105031614	ENSELUP00000025649	ENSELUP00000002859	Coagulation factor VII.	Macrophage stimulating 1 receptor b.	0.599
LOC105019751	f2	ENSELUP00000025649	ENSELUP00000023415	Coagulation factor VII.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.770
LOC105019751	f5	ENSELUP00000025649	ENSELUP00000018756	Coagulation factor VII.	Coagulation factor V; Belongs to the multicopper oxidase family.	0.621
LOC105019751	met	ENSELUP00000025649	ENSELUP00000034052	Coagulation factor VII.	MET proto-oncogene, receptor tyrosine kinase.	0.599
LOC105019751	serpina10	ENSELUP00000025649	ENSELUP00000008887	Coagulation factor VII.	Si:ch1073-416d2.3; Belongs to the serpin family.	0.646
LOC105019751	serpinc1	ENSELUP00000025649	ENSELUP00000027317	Coagulation factor VII.	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.	0.739
LOC105019751	tdo2	ENSELUP00000025649	ENSELUP00000021538	Coagulation factor VII.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.870
LOC105021910	LOC105019751	ENSELUP00000018165	ENSELUP00000025649	Uncharacterized protein.	Coagulation factor VII.	0.581
LOC105021910	f2	ENSELUP00000018165	ENSELUP00000023415	Uncharacterized protein.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.727
LOC105021910	serpinc1	ENSELUP00000018165	ENSELUP00000027317	Uncharacterized protein.	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.	0.601
LOC105024430	LOC105019751	ENSELUP00000029003	ENSELUP00000025649	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Coagulation factor VII.	0.621
LOC105024430	f2	ENSELUP00000029003	ENSELUP00000023415	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.906
LOC105024430	serpina10	ENSELUP00000029003	ENSELUP00000008887	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.	Si:ch1073-416d2.3; Belongs to the serpin family.	0.443