STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apcAPC regulator of WNT signaling pathway. (2756 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.996
LOC105030252
Uncharacterized protein.
   
 0.984
axin1
Axin 1.
   
 0.984
AXIN2
Axin 2.
   
 0.983
LOC105026129
Axin 2 (conductin, axil).
   
 0.983
skp1
Uncharacterized protein; Belongs to the SKP1 family.
     
 0.964
dvl3
Dishevelled segment polarity protein 3b.
    
 0.948
LOC105010801
Dishevelled segment polarity protein 2.
    
 0.948
LOC105020639
Uncharacterized protein.
    
 0.948
dvl1
Dishevelled segment polarity protein 1a.
    
 0.948
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.